Nowadays combined T3 and T4 therapies are often prescribed to mimic the normal function of the thyroid glands, people who undergo these therapies obtain a significant improvement in their quality of life compared to the previous situation, but there is a way to improve even more the well-being sensation.
As it can be seen in the publication of the New England Journal of Medicine of 1999, in the article by Bunevicius et al. , the replacement of part of the T4 in therapies with a high amount of it (doses greater than 50mcg per day of T4) by T3 caused a large number of improvements in patients such as:
- Greater energy.
- Better concentration.
- An improvement in well-being.
- Reduction of side effects such as: dizziness, heat, chills, blurred vision and nausea among others.
- The protocol consists of reducing the dose of T4 by 50mcg and replacing it with 12.5mcg of T3.
- As we can see the reduction is given in a percentage of 4:1 therefore to avoid possible side effects I would recommend gradually decreasing the dose of T4 by 4mcg for each 1mcg of T3 included until reaching the replacement of 50mcg of T4 for 12.5mcg of T3.