Under the scope: RAD 140

It is a third generation SARM, being investigated by Radius Health with the aim of serving for TRT and as a treatment for prostate or breast cancer with the fewest possible side effects.


  • Has a potency similar to testosterone, mg for mg has a great potency.
  • Has a half-life of 60 hours (contrary to the 14 that are often said).
  • Has a high affinity for androgen receptors, increasing the oxidation of fatty acids.
  • Does not aromatize or convert to DHT therefore it has no androgenic capacity.
  • Raises transaminases much less than the rest of the less potent SARMS.
  • Basal metabolic rate increases.
  • Has a neuroprotective effect (increases the feeling of well-being and libido).


  • By increasing the dose it loses the selectivity characteristic of SARMS.
  • The lipid profile worsens.
  • Elevation of transaminases.


It is a very powerful SARM with a lot of different benefits and few side effects, doses of 14-50mg are recommended depending on weight and goals and its half-life is 60 hours.

Marco D. Angelo

PhD in biochemistry, specialized in enzymology and metabolic biochemistry with a background in pharmacology, he works in a molecular biology laboratory and in his spare time works as a high-performance trainer in addition to assisting other coaches.