MOTS-c a promising PED

MOTS-c: a promising PED

MOTS-c (Mitochondrial Open reading frame of the Twelve S rRNA-c) is a 16-amino-acid, mitochondrial analogue peptide that has recently garnered some attention in bodybuilding circles thanks to its seemingly miraculous properties.

The role of MOTS-c is to regulate metabolic functions for the production of energy. It’s mechanism of action is incredibly complicated and not very well-understood, but we can get a good idea of its effects by reading the preclinical trials it has gone through and the anecdotal information shared by users who have experimented with it.

Benefits of MOTS-c

The benefits of this peptide are many, but chances are it has other properties that have not been studied yet.

In a nutshell, we could say that MOTS-c’s main function is to promote metabolic homeostasis. Therefore, it’s main benefits are:

  • A reduction of blood sugar levels and insulin resistance.
  • Improved metabolism, which translates to easier fat loss.
  • Fatty acid metabolism.
  • Greater energy levels.
  • Improved glucose disposal.
  • Prevents osteoporosis.
  • Improves cardiovascular endurance.
  • May help with muscle growth.

In other words, this peptide optimizes some of the primary metabolic pathways involved in fat loss, physical performance and muscle growth.

Side-effects of MOTS-c

MOTS-c appears to have no side-effects when used properly, but it would be safe to assume that it can cause hypoglycemia if abused or combined with compounds like Metformin, Insulin or even Berberine.

More scientific and anecdotal data is necessary to be able to determine other possible side-effects.

How to use it

Inject anywhere from 1 to 3mg subcutaneously every day. There is not set or agreed upon cycle length, but keep it to an effective minimum to prevent unexpected issues.

In conclusion, MOTS-C is a promising PED that could be extremely beneficial to any bodybuilder regardless of what their short-term and long-term goals are.


William Davis

William has been studying and experimenting with bodybuilding pharmacology for over 6 years. After being an independent researcher for all these years, he has decided to share his knowledge with the bodybuilding community through his science-based articles. His approach to enhanced bodybuilding can be summed up in the saying “less is more”, as he believes that prioritizing harm mitigation and looking for ways to maximize the positives is the key to longevity in bodybuilding.

Leave a Reply

Your email address will not be published. Required fields are marked *