Cardarine (also known as GW-501516 and Endurobol) is a PPARδ receptor agonist that was developed by Ligand Pharmaceuticals and GSK for the treatment of metabolic and cardiovascular diseases. Unfortunately, it was abandoned after a controversial study in which rats developed cancer came out. Cardarine works by activating PPAR-Delta receptors, which in turn upregulate the expression […]Read More
3,5-Diiodothyronine 3,5-Diiodothyronine, also known as T2, 3,5-T2 or 3,5-Diiodo-LThyronine, is a metabolite of T3. On a mcg-to-mcg basis, T2 is much weaker than T3, but studies have shown that T3 can be highly effective at burning fat by accelerating metabolism, stimulating mitochondrial function, and increasing lipid mobilization. Even though there is very little scientific or […]Read More
In the world of nutrition, carbohydrates have often been painted with a broad brush—either vilified as the root of all dietary evils or hailed as essential fuel for the body. The truth, as is often the case, lies somewhere in between. Enter the One Hundred Gram Carb Cure, a balanced approach to carbohydrate intake that […]Read More
The thyroid gland, a small butterfly-shaped organ located at the base of our necks, plays a crucial role in regulating our body’s metabolism, energy levels, and overall performance. For bodybuilders, maintaining optimal thyroid health and manipulating thyroid function is essential, as it directly influences muscle growth, fat loss, and workout efficiency. In this article, we’ll […]Read More
Tirzepatide is a promising new drug belonging to the GLP-1 and GIP Receptor Agonist classes of drugs that has recently been approved by the US Food and Drug Administration (FDA) for the treatment of type 2 diabetes. It appears as an alternative to Ozempic (Semaglutide), which has rapidly become a popular weight-loss medication among […]Read More
B-AET, also known as Beta-Androstenetriol, is a DHEA metabolite that offers incredible health benefits, anti-catabolism, and fat-loss. Unfortunately, chances are you’ve never heard of this compound before. Fortunately, the reason why you’ve never heard of it before is that it’s incredibly hard to find, and not because it has some major drawback that makes it […]Read More
MOTS-c (Mitochondrial Open reading frame of the Twelve S rRNA-c) is a 16-amino-acid, mitochondrial analogue peptide that has recently garnered some attention in bodybuilding circles thanks to its seemingly miraculous properties. The role of MOTS-c is to regulate metabolic functions for the production of energy. It’s mechanism of action is incredibly complicated and not very […]Read More
Tesofensine, also known as NS2330, is technically classified as a presynaptic serotonin–noradrenaline–dopamine reuptake inhibitor. Its pharmacological action leads to the inhibition of the reabsorption of these neurotransmitters by the central nervous system, resulting in reduced feelings of hunger. This compound primarily acts as an appetite suppressant while also influencing fat oxidation and resting energy expenditure. […]Read More
Yohimbine is a potent fat-burning agent that is known for 3 things: Being extremely effective at reducing stubborn fat, improving libido significantly and causing terrible fever-like symptoms in most users. Rauwolscine (alpha-yohimbine) is an isomer of Yohimbine that is slowly gaining popularity as a cleaner, safer yet more effective alternative to its parent compound. It […]Read More
Sobetirome (also known as GC-1) is a Thyroid Receptor Beta-Specific Agonist drug that was developed as a potential alternative to T3 and T4 for the treatment of hypothyroidism. As you know, the thyroid hormones T3 and T4 regulate metabolism and other important physiological processes within the body, so being thyroid deficient is not only incredibly […]Read More
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