Cardarine (also known as GW-501516 and Endurobol) is a PPARδ receptor agonist that was developed by Ligand Pharmaceuticals and GSK for the treatment of metabolic and cardiovascular diseases. Unfortunately, it was abandoned after a controversial study in which rats developed cancer came out. Cardarine works by activating PPAR-Delta receptors, which in turn upregulate the expression […]Read More
3,5-Diiodothyronine 3,5-Diiodothyronine, also known as T2, 3,5-T2 or 3,5-Diiodo-LThyronine, is a metabolite of T3. On a mcg-to-mcg basis, T2 is much weaker than T3, but studies have shown that T3 can be highly effective at burning fat by accelerating metabolism, stimulating mitochondrial function, and increasing lipid mobilization. Even though there is very little scientific or […]Read More
In bodybuilding, joint stiffness can occur due to intense training and the use of anabolic-androgenic steroids (AAS). AAS use may lead to joint discomfort by altering fluid retention and collagen synthesis, resulting in restricted movement and pain. This can affect performance, recovery, and overall joint health, while also facilitating the occurrence of injuries. Therefore, one […]Read More
Anabolic-androgenic steroids (AAS) can significantly impact cholesterol levels, increasing the risk of cardiovascular diseases. If you are an athlete who values health, longevity and being your best self, you must understand what cholesterol is and keep track of it… Total cholesterol This parameter measures the total amount of cholesterol in your blood. It is NOT […]Read More
The use of Anabolic Steroids and other PEDs leads to an increase in blood thickness. This is extremely dangerous, as it causes an increase in blood pressure that can cause dizziness, headaches, nosebleeds and other annoying side-effects short-term, but also cardiac hypertrophy and even deadly cardiovascular events in the long run. Donating blood during and/or […]Read More
If you are a bodybuilder, chances are your gut health is suboptimal. Years of eating copious amounts of food can cause gut distension and mess up your digestive system. Pair that with the use of all kinds of supplements and oral PEDs and you’ve got yourself a recipe for constant flatulence, irregular bowel movements, diarrhea, […]Read More
In the realm of cardiovascular health, statins have emerged as a controversial yet widely prescribed class of drugs. These cholesterol-lowering medications have sparked debates among healthcare professionals and patients alike, raising questions about their efficacy, potential benefits and potential side-effects. After reading this Inner Sanctum article, you will understand what statins are, how they work, […]Read More
Bromocriptine (also known as Parlodel) is a dopamine agonist similar to Cabergoline. It was developed and is still being prescribed for the treatment of parkinson’s, prolactinomas, diabetes and addiction withdrawal. Bromocriptine can be very useful in a bodybuilding context thanks to its prolactin-lowering and hunger-inhibiting properties, which make it a perfect addition to a Nandrolone, […]Read More
5-Amino-1MQ is a short-chain peptide that has shown promising results in the treatment of obesity. It is slowly growing in popularity as an excellent oral fat-burner that can reduce body fat significantly without causing serious side-effects. What does 5-AMINO-1MQ do? 5-Amino-1MQ is a membrane-permeable peptide that works by inhibiting NNMT (Nicotinamide N-methyltransferase) and increasing NAD+. […]Read More
In order to accomplish fitness goals, whether it’s building muscle, losing weight, improving overall health, or simply aiming at better overall performance, tracking progress is a crucial aspect that is overlooked way too often. While workouts, healthy eating and a proper hormonal environment are all essential components, quantifiable data provides invaluable insights to your fitness […]Read More
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