Adipotide: dangerous fat-burner or miracle drug?
Adipotide (Prohibitin-targeting Peptide 1) is a peptide that was originally developed for the treatment of cancer. However, animal studies found that it could destroy fat cells and cause fat loss. Unfortunately, this drug can be very dangerous if misused, hence its infamous reputation in bodybuilding circles.
What does Adipotide do?
In a nutshell, Adipotide targets the blood vessels that supply fat cells with the blood and nutrients they need to survive. By cutting off this blood supply, Adipotide causes fat cells to die, leading to a reduction in overall fat mass.
The benefits of Adipotide
The benefits of Adipotide are really simple: It makes fat loss extremely easy as long as one is not on a surplus, and it does not cause the anxiety, high body temperature or cardiovascular side-effects that other fat-burners are known for.
The side-effects of Adipotide
Unfortunately, the side-effects of Adipotide will put most people off from using it. In fact, the late bodybuilder Bostin Loyd (RIP) sustained serious kidney injuries after using it, which combined with the damage they had already taken as a result of AAS use led him to suffer from kidney failure.
Furthermore, there is very little scientific and anecdotal information about it, so we don’t know all of its possible side-effects. Here’s what’s known so far:
- Adipotide causes dehydration.
- Adipotide is nephrotoxic (kidney toxic).
- Adipotide may cause brain fog and headaches.
Adipotide protocol for bodybuilders
I do not recommend using Adipotide because there is very little research on it, but based on all the information I have been able to gather over the last few months, here’s how I would take it if I really wanted to:
0.5mg/day injected subcutaneously for a week, then a week off, then 0.5m/day subcutaneously for another week.
That’s it, anecdotal reports showing serious kidney damage were often using 2 to 5mg/day, so keeping the dose low seems reasonable.
I would not stop drinking water and ensuring optimal electrolyte balance, and I would take kidney protecting supplements like NAC and preferably injectable glutathione. I would also supplement with nootropics like Oxiracetam, Noopept and Alpha-GPC to prevent brain fog and headaches, as well as Fish Oil Omega-3 for further neuroprotection.
Should you take Adipotide?
Probably not. But if you are a very experienced bodybuilder who has tried every other potentially dangerous drug under the sun and you happen to have very healthy kidneys I won’t blame you if you decide to give it a shot.
Adipotide is a fascinating yet unnecessarily dangerous fat-burning peptide that has made some waves in the enhanced bodybuilding space. In my opinion, the pros do not outweigh the cons, so I would avoid it and opt for safer alternatives like AOD-9604 and HGH Fragment 176-191.
