Yohimbine 101: eliminate stubborn fat

Yohimbine is an extract of Yohimbe Bark, belonging to a tree that can only be found in certain parts of Africa. This bark has been used by the local population as an aphrodisiac for centuries, but its properties go beyond just improving sexual function.

What does yohimbine do?

Yohimbine is not backed by a lot of research, but it is known to interact with many different receptors, primarily alpha-1 and alpha-2 adrenoceptors, which it blocks.

By blocking these receptors, Yohimbine increases heart rate and blood pressure, it lowers blood sugar levels, and it facilitates the use of stored fat as a source of energy.

The mechanism of action behind the sexual performance benefits of Yohimbine is not fully understood.

The benefits of yohimbine as a ped

Here’s what you can expect from Yohimbine:

  • Yohimbine will burn fat by increasing heart rate and energy expenditure.
  • Yohimbine will facilitate the loss of stubborn fat by blocking alpha adrenoceptors.
  • Yohimbine will increase energy and focus.
  • Yohimbine will improve memory and information retention.
  • Yohimbine will lower blood sugar levels and fight insulin resistance.
  • Yohimbine will improve libido and erectile function.

Besides these benefits, there is also some evidence to suggest that it can fight blood-clotting, act as a painkiller and improve renal function.

The side-effects of yohimbine

The side-effects of Yohimbine can be somewhat dangerous:

  • Yohimbine will increase heart rate and blood pressure.
  • Yohimbine will increase body temperature and sweating.
  • Yohimbine may cause anxiety.
  • Yohimbine may cause jitters (like Clenbuterol).
  • Yohimbine may cause insomnia.
  • Yohimbine may cause dizziness, nausea and headaches.

Keep in mind that Yohimbine is not as well-researched as other fat-burners like Clenbuterol, but it would be safe to assume that it can also have a serious effect on heart health in the long run.

Yohimbine protocol for bodybuilders

A lot of people feel like training on Yohimbine is nearly impossible due to the anxiety, and they opt for using it before fasted cardio instead. That’s what I would personally recommend.

Take Yohimbine after waking up and before fasted morning cardio. You should be using 5m/day for the first two weeks, then increase to 10mg/day during weeks 3 & 4, and finally go up to 15mg/day during weeks 5 & 6.

If you take short breaks in between, you can remain on lower doses for long periods of time, but you will miss out on fat-burning potential.

The half-life is short at around 2 hours, so you can offset the side-effects by doing cardio, drinking a lot of water and using vasodilators like L-Arginine, L-Citrulline or even Tadalafil / Sildenafil to keep your blood pressure in check.

Topical formulations exist and they tend to have a milder negative effect on your blood pressure, heart rate and anxiety. I would advise people to use that first, by just rubbing a dollar coin-sized amount of cream on their abs before fasted cardio.


Like Clenbuterol, Yohimbine is for experienced athletes who know what they are doing. You can probably have great results with the protocol above if you are willing to feel uncomfortable while you are on it, but don’t use it if you are not lean already.

The selling point of Yohimbine is that it can burn stubborn fat, so use it towards the end of your cutting cycles when it’s needed the most.


William Davis

William has been studying and experimenting with bodybuilding pharmacology for over 6 years. After being an independent researcher for all these years, he has decided to share his knowledge with the bodybuilding community through his science-based articles. His approach to enhanced bodybuilding can be summed up in the saying “less is more”, as he believes that prioritizing harm mitigation and looking for ways to maximize the positives is the key to longevity in bodybuilding.

Leave a Reply

Your email address will not be published. Required fields are marked *