Cardarine (also known as GW-501516 and Endurobol) is a PPARδ receptor agonist that was developed by Ligand Pharmaceuticals and GSK for the treatment of metabolic and cardiovascular diseases. Unfortunately, it was abandoned after a controversial study in which rats developed cancer came out. Cardarine works by activating PPAR-Delta receptors, which in turn upregulate the expression […]Read More
3,5-Diiodothyronine 3,5-Diiodothyronine, also known as T2, 3,5-T2 or 3,5-Diiodo-LThyronine, is a metabolite of T3. On a mcg-to-mcg basis, T2 is much weaker than T3, but studies have shown that T3 can be highly effective at burning fat by accelerating metabolism, stimulating mitochondrial function, and increasing lipid mobilization. Even though there is very little scientific or […]Read More
MOTS-c (Mitochondrial Open reading frame of the Twelve S rRNA-c) is a 16-amino-acid, mitochondrial analogue peptide that has recently garnered some attention in bodybuilding circles thanks to its seemingly miraculous properties. The role of MOTS-c is to regulate metabolic functions for the production of energy. It’s mechanism of action is incredibly complicated and not very […]Read More
Sobetirome (also known as GC-1) is a Thyroid Receptor Beta-Specific Agonist drug that was developed as a potential alternative to T3 and T4 for the treatment of hypothyroidism. As you know, the thyroid hormones T3 and T4 regulate metabolism and other important physiological processes within the body, so being thyroid deficient is not only incredibly […]Read More
5-Amino-1MQ is a short-chain peptide that has shown promising results in the treatment of obesity. It is slowly growing in popularity as an excellent oral fat-burner that can reduce body fat significantly without causing serious side-effects. What does 5-AMINO-1MQ do? 5-Amino-1MQ is a membrane-permeable peptide that works by inhibiting NNMT (Nicotinamide N-methyltransferase) and increasing NAD+. […]Read More
T3 (triiodothyronine) is a naturally-occurring thyroid hormone that regulates metabolism, digestion, cognition, immunity and even sexual function to a small extent. This is a hormone that we all have and need in order to function optimally, but it can also be used exogenously to replace endogenous T3 levels in people with hypothyroidism, or as a […]Read More
Metformin is a popular medication that is commonly prescribed to treat type 2 diabetes and polycistic ovarian syndrome (PCOS). It is derived from galegine, a compound found in a plant known as Galega Officinalis. What does Metformin do? This drug works by inhibiting glucose production in the liver and inhibiting the actions of glucagon, a […]Read More
Bodybuilders are always on the lookout for new Performance Enhancing Drugs that can help them take their physique and performance to the next level. A drug that has grown in popularity in recent years is the stimulant / fat-burner known as DMHA (1,5-Dimethylhexylamine), which represents an incredible alternative to the now illegal (yet still widely […]Read More
Ephedrine is a sympathomimetic amine structurally related to amphetamines. Ephedrine is found in Ephedra, a plant found throughout Asia, Europe and America. Ephedrine is often prescribed for the treatment of Asthma and other respiratory diseases, and it’s also used to keep blood pressure from dropping during anesthesia. Ephedrine is also a stimulant that can increase […]Read More
Yohimbine is an extract of Yohimbe Bark, belonging to a tree that can only be found in certain parts of Africa. This bark has been used by the local population as an aphrodisiac for centuries, but its properties go beyond just improving sexual function. What does yohimbine do? Yohimbine is not backed by a lot […]Read More
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